Program description

This year's program extended beyond high-content imaging to explore biomolecular imaging & informatics more broadly construed. 

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Sunday, September 18, 2022

Sunday, September 18 was Education Day, with parallel tracks exploring best practices and unmet needs in biomolecular imaging & informatics. The annual Colloquium, entitled Challenges and opportunities in imaging data integration and analytics, was held that afternoon (all times US Eastern).

Track 1
(St. George A/B)
Track 2
(St. George C/D)
Track 3
(Staffordshire Ballroom)
1:00 – 1:50 p.m. Life beyond the pixels: Image analysis and machine learning for single-cell analysis—Peter Horvath (Biological Research Centre, Szeged & FIMM, Helsinki) Intro to 3D imaging and analysis for spheroid and organoid models—Alexandra Title (InSphero)

Sponsored by

Introduction to high-content imaging—Paul A. Johnston (University of Pittsburgh)
2:00 – 2:50 p.m. Software environments: Enabling integrated, scalable, and open 3D imaging—Eric Hawblitzel (Arivis)

Sponsored by

Microscopy: Advancements, and applications—Samantha Fore (Zeiss Research Microscopy Solutions)

Sponsored by

Introduction to assay statistics—Bartek Rajwa (Purdue University)
3:00 – 3:50 p.m. Introduction to spatial biology: Imaging and applications—Yunhao Bai (Stanford University) Automation and miniaturization of advanced 3D cell-based assays for drug screening—Tijmen Booij (ETH Zurich, NEXUS Personalized Health Technologies)

Sponsored by

Metrics and best practices for assay development and standardization—Joe Trask (PerkinElmer)

2022 Colloquium
Challenges and opportunities in imaging data integration and analytics
Sponsored by 

4:15 – 4:20 p.m. Introductory remarks—Gregory P. Way (University of Colorado)
4:20 – 4:25 p.m. An introduction to TissueGnostics—Russell Ulbrich (TissueGnostics)
4:25 – 4:45 p.m. Processing high-dimensional cell morphology representations with (open source) pycytominer—Gregory P. Way (University of Colorado)
4:45 – 4:50 p.m. Q & A
4:50 – 5:10 p.m. Integrating imaging with cloud longitudinal records—Vivian Neilley (Google)
5:10 – 5:15 p.m. Q & A
5:15 – 5:45 p.m. Panel discussion—Christina Baer (University of Massachusetts Chan Medical School), Anne Carpenter (Broad Institute), Santosh Hariharan (Pfizer), Peter Horvath (Biological Research Centre, Szeged & FIMM, Helsinki), Vivian Neilley (Google)
Monday, September 19, 2022
All times US Eastern.
8:30 – 6:30 p.m. Exhibit Hall open / Networking
8:30 – 9:00 a.m. Continental breakfast
9:00 – 10:00 a.m. Keynote presentation 1
Cancer rearranges the rules in tissue building blocks. A new class of targets for therapy?—Garry Nolan (Professor, Pathology, Baxter Laboratory, Stanford University)
10:00 – 10:15 a.m. Keynote Spotlight
Discovering meaningful data in multiplex tissue images through image analysis—Regan Baird (Visiopharm)

Sponsored by Visiopharm
10:15 – 10:45 a.m. Break for coffee & exhibit viewing
10:45 – 1:00 p.m. Session I — Integration of spatial image-omics with data analysis tools
Chairs: Don Apanovitch (Syngene), Sizun Jiang (Beth Israel Deaconess Medical Center)
10:45 – 11:15 a.m. Mapping the spatial architecture of human tissues in health and disease with multiplexed ion beam imaging—Erin McCaffrey (Stanford University)
11:15 – 11:45 a.m. AI-driven multimodal computational pathology—Faisal Mahmood (Harvard Medical School)
11:45 a.m. – 12:15 p.m. Matching cells across single-cell modalities – from sequencing to imaging—Bokai Zhu (Stanford University)
12:15 – 12:45 p.m. Decoding and visualizing tumor heterogeneity using interpretable AI—Heba Sailem (University of Oxford)
12:45 – 1:00 p.m. Spotlight
From image to results: Automated image capture, segmentation, & analysis of 3D-organoids using machine-learning techniques—Ryan Jacobs (Zeiss Microscopy)

Sponsored by Zeiss
1:00 – 1:45 p.m. Luncheon Spotlights
Two concurrent Luncheon Spotlights will be held in St. George A/B and St. George C/D on the Conference Level. Box lunches will be provided to Spotlight attendees.

Spotlight 1 (St. George A/B) Spotlight 2 (St. George B/C)
Current and future approaches to AI-powered analysis of high-content screens—Cameron Scott & Daniel Siegismund (Genedata) Single cell spatially resolved transcriptomic imaging with MERSCOPE for molecular and cell atlasing —Jiang He (Vizgen)
Sponsored by Genedata
Sponsored by Vizgen
1:45 – 4:30 p.m. Session II — Enhancing translatability with imaging: 3D models, co-culture, and organ-on-a-chip
Chairs: Jason Ekert (UCB), Scott Cribbes (PerkinElmer)
1:45 – 2:15 p.m. Self-organizing image analysis machines to differentiate cancer phenotypes—Chris Bakal (Institute of Cancer Research)
2:15 – 2:45 p.m. High-throughput 3D phenomics on a beach—Andrei Georgescu (CEO, Vivodyne)
2:45 – 3:00 p.m. Spotlight
Multiplex gene tagging with CRISPR-Cas9 for live high-content imaging—Oscar Perez
(Temple University, School of Pharmacy)

Sponsored by ExpressCells
3:00 – 3:30 p.m. Break for coffee & exhibit viewing
3:30 – 4:00 p.m. Imaging complex models in target discovery: Balancing information content with throughput—Erin Edwards (GSK)
4:00 – 4:30 p.m. Short talks (selected from poster abstracts)
Exploring the intricacies of DILI – Organoids, liver chips, and high-content imaging—Charles Zhang (University of Michigan)
Scalable hyperspectral artificial intelligence for real-time colonoscopy—William D. Oswald (University of South Alabama)
4:30 – 5:30 p.m. Exhibit viewing
5:30 – 6:30 p.m. Poster session & reception
Tuesday, September 20, 2022
All times US Eastern.
8:15 – 5:30 p.m. Exhibit Hall open / Networking
8:15 – 8:45 a.m. Continental breakfast
8:45 – 9:45 a.m. Keynote presentation 2
In biology, structure suits function: A mission to decode biology—Chris Gibson (CEO, Recursion Pharma)
9:45 – 10:00 a.m. Keynote Spotlight
Providing innovative workflows to advance discovery research—Joe Trask (PerkinElmer)

Sponsored by PerkinElmer
10:00 – 10:30 a.m. Break for coffee & exhibit viewing
10:30 a.m. – 12:45 p.m. Session III — Advances in high-content imaging: Next generation phenotypic screening assays
Chairs: Erin Edwards (GSK), David Shum (Institut Pasteur Korea), Steve Walker (Abbvie)
10:30 – 11:00 a.m. Advancing drug discovery by measuring protein dynamics through single particle tracking—Daniel Anderson (Eikon Therapeutics)
11:00 – 11:30 a.m. From development to translational applications of aggressive pediatric brain tumor models—Maria Vinci (Bambino Gesù Children’s Hospital–IRCCS, Italy)
11:30 a.m. – 12:00 p.m. AI-enabled multiplexed cardiomyopathy and proarrhythmia in vitro KIC assay of human iPSC-cardiomyocytes for early drug development—Jeffrey H. Price (Scintillon Institute & Vala Sciences, Inc.)
12:00 – 12:30 p.m. Short talks (selected from poster abstracts)
Morphological trajectory inference: Tracking cell state transitions and small-molecule perturbations—Rebecca Hughes (University of Edinburgh)
Novel analysis method for in-situ spatial phenotyping of cell populations in multimarker imagery—Jim Mansfield (Visiopharm)
12:30 – 12:45 p.m. Spotlight
Democratizing multiparameter high-content screening applications with the new CellInsight™ CX7 Pro Series—Nicholas M. Radio (Thermo Fisher Scientific)

Sponsored by Thermo Fisher Scientific
12:45 – 1:45 p.m. Luncheon (on your own) & exhibit viewing
1:45 – 4:30 p.m. Session IV — Artificial intelligence / machine learning in biomolecular imaging: Successes and challenges
Chairs: Gregory P. Way (University of Colorado), Heba Sailem (University of Oxford)
1:45 – 2:15 p.m. Unleashing the morpholome—Maddison Masaeli (CEO, DeepCell Bio)
2:15 – 2:45 p.m. Interpretable machine learning in microscopy—Assaf Zaritsky (Ben-Gurion University of the Negev)
2:45 – 3:00 p.m. Spotlight
10x your lab: High content analysis meets high-throughput screening—Maggie Vantangoli Policelli (Araceli)

Sponsored by Araceli Biosciences

3:00 – 3:30 p.m. Break for coffee & exhibit viewing
3:30 – 4:00 p.m. AI for precision histopathology: The road ahead—Nasir Rajpoot (University of Warwick)
4:00 – 4:30 p.m. President's Innovation Award presentation
Breaking the barriers of AI in biomedical research to boost scientific breakthrough—Estibaliz Gómez de Mariscal
(Instituto Gulbenkian de Ciência)
4:30 – 5:30 p.m. Poster & exhibit viewing
5:30 – 5:45 p.m. Awards ceremony and meeting close
5:45 – 6:15 p.m. SBI2 Annual General Meeting (open to all attendees)

2022 Exhibitors, Sponsors, & Partners