Program description
This year's program extended beyond high-content imaging to explore biomolecular imaging & informatics more broadly construed.
Sunday, September 18, 2022
Sunday, September 18 was Education Day, with parallel tracks exploring best practices and unmet needs in biomolecular imaging & informatics. The annual Colloquium, entitled Challenges and opportunities in imaging data integration and analytics, was held that afternoon (all times US Eastern).
| Track 1 (St. George A/B) |
Track 2 (St. George C/D) |
Track 3 (Staffordshire Ballroom) |
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| 1:00 – 1:50 p.m. | Life beyond the pixels: Image analysis and machine learning for single-cell analysis—Peter Horvath (Biological Research Centre, Szeged & FIMM, Helsinki) | Intro to 3D imaging and analysis for spheroid and organoid models—Alexandra Title (InSphero)
Sponsored by |
Introduction to high-content imaging—Paul A. Johnston (University of Pittsburgh) |
| 2:00 – 2:50 p.m. | Software environments: Enabling integrated, scalable, and open 3D imaging—Eric Hawblitzel (Arivis)
Sponsored by |
Microscopy: Advancements, and applications—Samantha Fore (Zeiss Research Microscopy Solutions)
Sponsored by |
Introduction to assay statistics—Bartek Rajwa (Purdue University) |
| 3:00 – 3:50 p.m. | Introduction to spatial biology: Imaging and applications—Yunhao Bai (Stanford University) | Automation and miniaturization of advanced 3D cell-based assays for drug screening—Tijmen Booij (ETH Zurich, NEXUS Personalized Health Technologies)
Sponsored by |
Metrics and best practices for assay development and standardization—Joe Trask (PerkinElmer) |
2022 Colloquium
Challenges and opportunities in imaging data integration and analytics
Sponsored by 
| 4:15 – 4:20 p.m. | Introductory remarks—Gregory P. Way (University of Colorado) |
| 4:20 – 4:25 p.m. | An introduction to TissueGnostics—Russell Ulbrich (TissueGnostics) |
| 4:25 – 4:45 p.m. | Processing high-dimensional cell morphology representations with (open source) pycytominer—Gregory P. Way (University of Colorado) |
| 4:45 – 4:50 p.m. | Q & A |
| 4:50 – 5:10 p.m. | Integrating imaging with cloud longitudinal records—Vivian Neilley (Google) |
| 5:10 – 5:15 p.m. | Q & A |
| 5:15 – 5:45 p.m. | Panel discussion—Christina Baer (University of Massachusetts Chan Medical School), Anne Carpenter (Broad Institute), Santosh Hariharan (Pfizer), Peter Horvath (Biological Research Centre, Szeged & FIMM, Helsinki), Vivian Neilley (Google) |
Monday, September 19, 2022
All times US Eastern.
| 8:30 – 6:30 p.m. | Exhibit Hall open / Networking | ||||||
| 8:30 – 9:00 a.m. | Continental breakfast | ||||||
| 9:00 – 10:00 a.m. | Keynote presentation 1 Cancer rearranges the rules in tissue building blocks. A new class of targets for therapy?—Garry Nolan (Professor, Pathology, Baxter Laboratory, Stanford University) |
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| 10:00 – 10:15 a.m. | Keynote Spotlight Discovering meaningful data in multiplex tissue images through image analysis—Regan Baird (Visiopharm)
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| 10:15 – 10:45 a.m. | Break for coffee & exhibit viewing | ||||||
| 10:45 – 1:00 p.m. | Session I — Integration of spatial image-omics with data analysis tools Chairs: Don Apanovitch (Syngene), Sizun Jiang (Beth Israel Deaconess Medical Center) |
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| 10:45 – 11:15 a.m. | Mapping the spatial architecture of human tissues in health and disease with multiplexed ion beam imaging—Erin McCaffrey (Stanford University) | ||||||
| 11:15 – 11:45 a.m. | AI-driven multimodal computational pathology—Faisal Mahmood (Harvard Medical School) | ||||||
| 11:45 a.m. – 12:15 p.m. | Matching cells across single-cell modalities – from sequencing to imaging—Bokai Zhu (Stanford University) | ||||||
| 12:15 – 12:45 p.m. | Decoding and visualizing tumor heterogeneity using interpretable AI—Heba Sailem (University of Oxford) | ||||||
| 12:45 – 1:00 p.m. | Spotlight From image to results: Automated image capture, segmentation, & analysis of 3D-organoids using machine-learning techniques—Ryan Jacobs (Zeiss Microscopy)
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| 1:00 – 1:45 p.m. | Luncheon Spotlights Two concurrent Luncheon Spotlights will be held in St. George A/B and St. George C/D on the Conference Level. Box lunches will be provided to Spotlight attendees.
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| 1:45 – 4:30 p.m. | Session II — Enhancing translatability with imaging: 3D models, co-culture, and organ-on-a-chip Chairs: Jason Ekert (UCB), Scott Cribbes (PerkinElmer) |
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| 1:45 – 2:15 p.m. | Self-organizing image analysis machines to differentiate cancer phenotypes—Chris Bakal (Institute of Cancer Research) | ||||||
| 2:15 – 2:45 p.m. | High-throughput 3D phenomics on a beach—Andrei Georgescu (CEO, Vivodyne) | ||||||
| 2:45 – 3:00 p.m. | Spotlight Multiplex gene tagging with CRISPR-Cas9 for live high-content imaging—Oscar Perez (Temple University, School of Pharmacy)
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| 3:00 – 3:30 p.m. | Break for coffee & exhibit viewing | ||||||
| 3:30 – 4:00 p.m. | Imaging complex models in target discovery: Balancing information content with throughput—Erin Edwards (GSK) | ||||||
| 4:00 – 4:30 p.m. | Short talks (selected from poster abstracts) Exploring the intricacies of DILI – Organoids, liver chips, and high-content imaging—Charles Zhang (University of Michigan) |
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| Scalable hyperspectral artificial intelligence for real-time colonoscopy—William D. Oswald (University of South Alabama) | |||||||
| 4:30 – 5:30 p.m. | Exhibit viewing | ||||||
| 5:30 – 6:30 p.m. | Poster session & reception | ||||||
Tuesday, September 20, 2022
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| 8:15 – 5:30 p.m. | Exhibit Hall open / Networking | ||||||
| 8:15 – 8:45 a.m. | Continental breakfast | ||||||
| 8:45 – 9:45 a.m. | Keynote presentation 2 In biology, structure suits function: A mission to decode biology—Chris Gibson (CEO, Recursion Pharma) |
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| 9:45 – 10:00 a.m. | Keynote Spotlight Providing innovative workflows to advance discovery research—Joe Trask (PerkinElmer)
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| 10:00 – 10:30 a.m. | Break for coffee & exhibit viewing | ||||||
| 10:30 a.m. – 12:45 p.m. | Session III — Advances in high-content imaging: Next generation phenotypic screening assays Chairs: Erin Edwards (GSK), David Shum (Institut Pasteur Korea), Steve Walker (Abbvie) |
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| 10:30 – 11:00 a.m. | Advancing drug discovery by measuring protein dynamics through single particle tracking—Daniel Anderson (Eikon Therapeutics) | ||||||
| 11:00 – 11:30 a.m. | From development to translational applications of aggressive pediatric brain tumor models—Maria Vinci (Bambino Gesù Children’s Hospital–IRCCS, Italy) | ||||||
| 11:30 a.m. – 12:00 p.m. | AI-enabled multiplexed cardiomyopathy and proarrhythmia in vitro KIC assay of human iPSC-cardiomyocytes for early drug development—Jeffrey H. Price (Scintillon Institute & Vala Sciences, Inc.) | ||||||
| 12:00 – 12:30 p.m. | Short talks (selected from poster abstracts) Morphological trajectory inference: Tracking cell state transitions and small-molecule perturbations—Rebecca Hughes (University of Edinburgh) |
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| Novel analysis method for in-situ spatial phenotyping of cell populations in multimarker imagery—Jim Mansfield (Visiopharm) | |||||||
| 12:30 – 12:45 p.m. | Spotlight Democratizing multiparameter high-content screening applications with the new CellInsight™ CX7 Pro Series—Nicholas M. Radio (Thermo Fisher Scientific)
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| 12:45 – 1:45 p.m. | Luncheon (on your own) & exhibit viewing | ||||||
| 1:45 – 4:30 p.m. | Session IV — Artificial intelligence / machine learning in biomolecular imaging: Successes and challenges Chairs: Gregory P. Way (University of Colorado), Heba Sailem (University of Oxford) |
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| 1:45 – 2:15 p.m. | Unleashing the morpholome—Maddison Masaeli (CEO, DeepCell Bio) | ||||||
| 2:15 – 2:45 p.m. | Interpretable machine learning in microscopy—Assaf Zaritsky (Ben-Gurion University of the Negev) | ||||||
| 2:45 – 3:00 p.m. | Spotlight 10x your lab: High content analysis meets high-throughput screening—Maggie Vantangoli Policelli (Araceli)
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| 3:00 – 3:30 p.m. | Break for coffee & exhibit viewing | ||||||
| 3:30 – 4:00 p.m. | AI for precision histopathology: The road ahead—Nasir Rajpoot (University of Warwick) | ||||||
| 4:00 – 4:30 p.m. | President's Innovation Award presentation Breaking the barriers of AI in biomedical research to boost scientific breakthrough—Estibaliz Gómez de Mariscal (Instituto Gulbenkian de Ciência) |
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| 4:30 – 5:30 p.m. | Poster & exhibit viewing | ||||||
| 5:30 – 5:45 p.m. | Awards ceremony and meeting close | ||||||
| 5:45 – 6:15 p.m. | SBI2 Annual General Meeting (open to all attendees) | ||||||
2022 Exhibitors, Sponsors, & Partners
